PRECISION CANCER THERAPIES VOL 1 TARGETING ONCOGENIC DRIVERS AND SIGNALING PATHWAYS IN LYMPHOID MALI

TARGETING ONCOGENIC DRIVERS AND SIGNALING PATHWAYS IN LYMPHOID MALIGNANCIES

From Concept to Practice - Precision Cancer Therapy Volume 1

"Targeting Oncogenic Drivers and Signaling Pathways in Lymphoid Malignancies: From Concept to Practice" focuses on lymphoma, an area which has seen a remarkable number of breakthroughs in the...

Lire la suite keyboard_arrow_right

Auteur(s) Owen O'Connor, Stephen M Ansell, John F. Seymour
Éditeur WILEY
Date 04/05/2023
Pages 512
Taille 21 x 27
Type Relié
ISBN 9781119819929

Description détaillée : TARGETING ONCOGENIC DRIVERS AND SIGNALING PATHWAYS IN LYMPHOID MALIGNANCIES

Targeting Oncogenic Drivers and Signaling Pathways in Lymphoid Malignancies: From Concept to Practice focuses on lymphoma, an area which has seen a remarkable number of breakthroughs in the ongoing development of precision cancer therapies.

Each section on a specific biology or class of drugs has an introductory chapter written by an authority in the field, exclusively focused on the science and its relevance to cancer biology. This approach addresses the need for scientists, physicians, and the private sector to understand the broader context of the extraordinary advances that have produced such astonishing advances in the disease.

  

What is the Content of "Targeting Oncongenic Drivers and Signaling Pathways in Lymphoid Malignancies" ?

The work primarily focuses on how to understand and translate fundamental principles of basic science into information that can be directly applied to patients – hence the subtitle, From Concept to Practice.

To aid in readers’ comprehension, the first page of each chapter contains a box entitled ‘Take Home Points’. This short text will highlight the major unique points about the information contained within the chapter.

Some of the key topics addressed in the work are as follows:

  • Biological basis of the lymphoid malignancies: fundamental principles of lymphomagenesis and molecular classification of lymphoid malignancies
  • Targeting programmed cell death: principles for understanding the many types of cell death and promising combinations of drugs targeting apoptosis
  • Targeting the PI3K pathway: understanding the intricacies of this complex biology and precisely how targeted drugs can be leveraged therapeutically
  • Targeting the cancer epigenome: pharmacologic features of drugs targeting the epigenome and future prospects for targeting various aspects of epigenetic control
  • Targeting the tumour proteome: understanding the mechanisms of protein degradation in cancer including both older drugs like proteasome inhibitors, and newer PROTAC based approaches

Written primarily for scientists and physicians in both the public and private sectors, Targeting Oncogenic Drivers and Signaling Pathways in Lymphoid Malignancies: From Concept to Practice is a comprehensive reference work for those interested in the growing area of Precision Cancer Therapies.

Seamlessly integrating the basic and applied science, this volume will be an indispensable reference for those interested in translating the most important advances in science to innovative novel treatments for patients.

Who are the Authors of "Targeting Oncongenic Drivers and Signaling Pathways in Lymphoid Malignancies" ?

Owen A. O’Connor, M.D., Ph.D. is an American Cancer Society Research Professor at the University of Virginia Comprehensive Cancer Center. He completed his training in Internal Medicine at the New York Presbyterian Hospital at Weill Cornell University Medical School, a Fellowship in Hematology and Oncology at Memorial Sloan Kettering Cancer Center and a Fellowship in Clinical Pharmacology at Weill Cornell. He has been recognized as one of the Top Physicians in Cancer in the U.S. and is recognized by the Irish Government as one of the top 50 Irish Americans in Science and Medicine.

Stephen M. Ansell, M.D., Ph.D. is the Dorotha W. and Grant L. Sundquist Professor of Hematologic Malignancies Research and the Chair of the Division of Hematology at Mayo Clinic. He received his medical degree from the University of Pretoria, South Africa and then completed a fellowship in Hematology and Medical Oncology at Mayo Clinic. His research focuses on optimizing antitumor immune function in B-cell malignancies. He received the Ernst Beutler Award from the American Society of Hematology in 2021 in recognition of his work.

John F. Seymour MBBS Ph.D. heads the Department of Haematology of the Peter MacCallum Cancer Centre & the Royal Melbourne Hospital and is Professor of Medicine at the University of Melbourne. He completed a translational research fellowship at the MD Anderson Cancer Center in Houston, and has received their Distinguished Alumnus award. His work is focused on new drug development in lymphoid malignancies. He was awarded Membership of the Order of Australia, and elected to the Australian Academy of Health and Medical Sciences for his contributions to the field.

Auteur(s): TARGETING ONCOGENIC DRIVERS AND SIGNALING PATHWAYS IN LYMPHOID MALIGNANCIES

Owen O'Connor
Stephen M Ansell
176,30 €

Sur commande

Expédition sous 10 à 20 jours

176,30 €

Bénéficiez de la remise de 5% en choisissant le retrait en magasin

 
Livraison à 0.01€ à partir de 35€

d'achats en France Métropolitaine

 
Satisfait ou remboursé

sous 14 jours ouvrés

 
Paiements sécurisés

3D Secure

 
Service client

Lundi au Vendredi : de 10h à 18h30
au 04 67 63 62 19 ou par email