Clinical immunology, 6th edition

Clinical Immunology 6

Clinical immunology, 6th edition

Offering unique, comprehensive coverage of both basic science and clinical scenarios, Clinical Immunology: Principles and Practice, 6th Edition , brings you up to date with every aspect of this...

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Pages 1344
Taille 21 x 27
Type Relié
ISBN 9780702081651

Description détaillée : Clinical immunology, 6th edition

It examines the molecular, cellular, and immunologic bases of immunologic diseases and their broader systemic implications; and includes complete coverage of all common and less common disorders.

Updated with all the latest immunologic research and clinical implications, including breakthrough immunotherapies and molecular-based treatment protocols, this fully revised edition provides authoritative guidance from some of the most respected global leaders in immunology in one complete, well-illustrated volume. 

What is the content of "Clinical Immunology 6th edition" ?

Key Features

  • Includes extensive revisions that reflect rapidly expanding research and clinical advances, including breakthrough drug and immunotherapies such as immune checkpoint inhibitors, immunotherapies for cancer, precision medicine, and transfusion medicine.   
  • Contains new chapters on COVID-19, immune responses, and the role of the immune system; immunoregulatory deficiencies; immune checkpoints; CAR T-cells, including new cellular-based immunotherapy; gene therapy, including CRISPR and gene selection; and a clinically-focused chapter on asthma. 
  • Provides new genetics content focused on data applications. 
  • Addresses notable advances in key areas such as the importance of the microbiota to normal immune system development and to the pathogenesis of immunologic and inflammatory diseases; relationships between the innate and adaptive immune systems; progress in rapid and cost-effective genomics; cell signaling pathways and the structure of cell-surface molecules; and many more.  
  • Covers hot topics such as the role of genetics and genomics in immune response and immunologic disease, atherosclerosis, recurrent fever syndromes, aging and deficiencies of innate immunity, the role of microbiota in normal immune system development and the pathogenesis of immunologic and inflammatory diseases, and novel therapeutics. 
  • Features a user-friendly format with color-coded boxes highlighting critical information on Key Concepts, Clinical Pearls, Clinical Relevance, and Therapeutic Principles. 
  • Summarizes promising research and development anticipated over the next 5-10 years with "On the Horizon" boxes and discussions of translational research. 
  • Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices. 

Who are the authors of "Clinical Immunology 6th edition" ?

Robert R. Rich, MD, Professor of Medicine and Microbiology, University of Alabama at Birmingham School of Medicine, Birmingham, AL, USA

Thomas A. Fleisher, MD, FAAAAI, FACAAI, Adjunct Professor of Pediatrics, USUHA, Chief, Department of Laboratory Medicine, NIH Clinical Center, National Institutes of Health, Bethesda MD, USA

Harry W. Schroeder Jr., II, MD, PhD, Professor of Medicine, Microbiology, and Genetics, Division of Clinical Immunology and Rheumatology, Director, UAB Program in Immunology, University of Alabama at Birmingham, Birmingham, AL, USA

Cornelia M. Weyand, MD, PhD, Professor of Medicine, Stanford University School of Medicine, Department of Medicine: Immunology and Rheumatology, Stanford, CA, USA 

David B. Corry and Jennifer M. Puck

Sommaire : Clinical immunology, 6th edition

1The human immune response
2Organization of the immune system
3Innate immunity
4Antigen receptor genes, gene products, and co-receptors/
5The major histocompatibility complex
6Antigens and Antigen Presentation
7B-cell development and differentiation
8Immunoglobulin Function
9T-Cell Development
10T-Cell Activation and Tolerance
11Helper T-Cell Subsets and Control of the Inflammatory Response
12Cytotoxic T Lymphocytes and Natural Killer Cells?
13Regulatory Immune Cells
14Cytokines and cytokine receptors
15Chemokines and chemokine receptors
16Lymphocyte adhesion and trafficking
17Death Pathways and Immunogenicity
18T-cell activation and tolerance
18Regulated cell death
18The Microbiota in Immunity and Inflammation
18Human Genomics in Immunology
19Regulatory RNA in Immunologic Diseases
20Immunometabolism
21Immune Deficiencies at the Extremes of Age
22Nutritional Modulation of Immune Function
22The Microbiota in Immunity and Inflammation
23Immunology of the Skin
24Immunology of Mucosal Surfaces
24Complement in host deficiencies and diseases
24Phagocyte deficiencies
24Mast cells, basophils, and mastocytosis
24Eosinophils and eosinophilia
25Host defenses to viruses
26Host defenses to intracellular bacteria
27Host defenses to extracellular bacteria including Spirochetes
28Host Defenses to Fungi
29Host defenses to spirochetes
29Host defenses to protozoa
30Host defenses to helminth infections
31Emerging Pandemic Infectious Disease Threats
32Approach to the Evaluation of the Patient with Suspected Immunodeficiency
33Human Genomics in Immunology
33Primary antibody deficiencies
34Primary T-cell immunodeficiencies
35Genetic disorders of IFNs-, IL-17, IL-18 and NF-?B-mediated immunity
36Hemophagocytic Lymphohistiocytosis
37Autoinflammatory Syndromes
38Immune Activation Disorders
39Neutrophils and Neutrophil Disorders
40Complement and Complement Disorders
41Human Immunodeficiency Virus Infection and Acquired Immunodeficiency Syndrome
42Autoantibody Mediated Phenocopies of Primary Immunodeficiency Diseases
43Allergic Airway Disease
44Mast Cells and Mast Cell Disorders
45Eosinophils and Eosinophilic Disorders
46Urticaria, angioedema, and anaphylaxis
47Allergic reactions to stinging and biting insects
48Atopic and contact dermatitis
49Food allergy
50Drug Hypersensitivity
51Allergic disorders of the eye
51Drug hypersensitivity
51 Occupational Respiratory Allergies
51Mechanisms of autoimmunity
52Systemic lupus erythematosus
53Rheumatoid arthritis
54Juvenile idiopathic arthritis
55Sjren syndrome
56Scleroderma-systemic sclerosis
57Inflammatory muscle diseases
58Spondyloarthritis
59Small and medium vessel primary vasculitis
60Large-vessel vasculitides
61Systemic autoinflammatory syndromes
61Antiphospholipid syndrome
62Immunohematologic disorders
63Bullous diseases of the skin and mucous membranes
64Immunology of psoriasis
65Myasthenia gravis
66Multiple sclerosis
67Autoimmune peripheral neuropathies
68Immunologic renal diseases
69Immunologic Diseases of the Cardiovascular System
70Autoimmune thyroid diseases
71Type 1 Diabetes
72Immunologic lung diseases
73Chronic Obstructive Pulmonary Disease and Emphysema
74Immunologic ocular disease
75Immunologic diseases of the gastrointestinal tract
76Inflammatory hepatobiliary diseases
77Tumor immunotherapy
77Lymphoid leukemias
78Lymphomas
79Monoclonal gammopathies
80Immune Responses to Solid Tumors and Immune Checkpoint tTerapy
81CAR T-Cell Therapy
82Immunoglobulin Therapy: Replacement and Immunomodulation
83Glucocorticoids
84Immunomodulating Drugs
85Protein Kinase Antagonists
86Biologic Response Modifiers
87Vaccines
88Allergen Immunotherapy of Allergic Disease
89Solid Organ Transplantation: Rejection, Immunosuppression and Tolerance
89Immune Checkpoint Therapy
90Allogeneic Transplantation for Immunodeficiency
91Gene Therapy fo Primary Immune deficiency Diseases
92Hematopoietic Stem Cell Transplantation for Malignant Diseases
93Flow cytometry
94Biological Modifiers of Inflammation
94Vaccines
94Immunotherapy of allergic disease
94Assessment of Functional Immune Responses in Lymphocytes
95Assessment of neutrophil function
96Assessment of human allergic diseases
App1 - Selected CD molecules and their characteristics
App2 - Laboratory reference values
98Molecular methods
98A3: Vaccine schedules

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